Statistics in Biomedics Start Date : 28-Sep-2013   End Date : 28-Sep-2013

A one day Workshop organized by the Department of Statistics, Chest Research Foundation, Pune 


Registrations now open!!! Register for the workshop.


ICONIC 2014 Start Date : 01-Feb-2014    End Date : 02-Feb-2014

ICONIC 2014: The first international Conference on Insights and Management of COPD.


Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death in the world and a major cause of morbidity and disability. COPD is undergoing a silent epidemic in India, with very little awareness and focus about the disease amongst patients, health care providers, health care policy makers and researchers.


Scientists and researchers especially from the western world have contributed immensely to knowledge generation in the field of epidemiology, pathophysiological mechanisms, prevention and treatment of COPD, and translation of this knowledge has majorly impacted COPD care across the world. In contrast, knowledge generation in the field of COPD has been very slow in India and it remains largely a neglected public health problem with very little emphasis on prevention. COPD, also, remains poorly diagnosed and treated in clinical practice causing immense suffering and death, and a huge economic loss for the country. Recently, a need has been expressed to develop a National COPD Prevention and Control Program in India. But this will require major inputs in terms of knowledge and operational issues, especially from western world with experience in curbing the menace of this global public health problem.


The main objective of this conference is  (a) to disseminate knowledge in order to improve the quality of care that we offer to patients of COPD (b) gain better understanding of environmental factors, early life exposure effects on lung development, respiratory infections, lung health of non smoker women due to indoor air pollution and co-morbidities in India associated with COPD (c) new directions for research and policy change that will help reduce the suffering and deaths due to COPD in India.


          Register for the conference at:



Ist national HOD meet Start Date : 30-Mar-2013    End Date : 30-Mar-2013

Chest Research Foundation is proud to announce the first ever Head of Department meet at Chest Research Foundation on 30th March 2013. 

This is an initiative to bring together the heads of medical colleges to brain storm on various issues in Respiratory medicine with a hope of bringing about a change in the perception about respiratory medicine.

Attendance is through invitation only. 

Study of Prevalence of COPD and Phenotypic Characterisation of Smoking and NonSmoking COPD in A Rural Setting in India Start Date : 06-Dec-2012    End Date : 06-Dec-2015

 Participating institutions

National Heart and Lung Institute (NHLI), Imperial College, London

Chest Research Foundation (CRF), Pune

Vadu Rural Health Program (VRHP), Pune

Co-ordinating investigators

Professor Peter Barnes
Head of Respiratory Medicine, NHLI, Imperial College

Dr Sundeep Salvi
Director, CRF

Dr Sanjay Juvekar
Public Health Scientist, VRHP

Other investigators

Imperial College

Professor Anthony Newman Taylor
Professor Malcolm Green
Professor Peter Burney
Dr Trevor Hansel


Dr Bill Brashier


Dr Siddhi Hirve


  • Study the prevalence of COPD in a rural population in India.
  • Assess the prevalence of COPD induced by cigarette smoking, bidi smoking and causes other than smoking.
  • Investigate the association between COPD prevalence and air pollution—indoors and outdoors.
  • Study and compare the cellular and mediator profile in the induced sputum of subjects with COPD caused by various factors.
  • Compare the pulmonary function parameters of subjects of COPD caused by exposure to different causes.
  • Compare the radiological findings of subjects of COPD caused by exposure to various causes.
  • Examine the effects of corticosteroids on pulmonary inflammatory biomarkers in COPD.


The study covers a total of 22 villages in the ambit of VRHP, located about 30 km from Pune city. This is predominantly an agricultural area, but there has been a recent growth of industries in this region. The total study population is over 75,000.


The study will be conducted in two phases.

Phase I

  • Prevalence of COPD in the study population using the Burden of Obstructive Lung Disease (BOLD) questionnaire and pre- and post-bronchodilator spirometry.
  • Measurement of ambient air pollutants (particulate matter less than 2.5 microns [PM2.5], particulate matter less than 10 microns [PM10], sulphur dioxide, nitrogen oxides and carbon monoxide) in the study region for one year.
  • Measurement of indoor air pollutants (PM10, PM2.5, SO2, NO, NO2 and CO) in homes using different cooking fuels.
  • Detailed characterization of particulate matter for organic and inorganic ions and metals from homes using different cooking fuels.
  • Global Positioning System (GPS) of the entire study population to determine spatial distribution of the prevalence of COPD and its association with air pollutants.

Phase II

  • Isolating a stratified sample of different COPD phenotype subjects (cigarette smoke exposure, bidi smoke exposure and chullah smoke exposure) diagnosed on the basis of BOLD methodology and selecting age matched controls, and subjecting to detailed phenotype analysis:
    • Spirometry, body plethysmography, impulse oscillometry, lung diffusion studies.
    • High Resolution CT scan and chest X-ray.
  • Sputum induction to study cellular and mediator profile:
    • Total and differential cell counts, IL-8, IL-6, TNF-?, etc.
    • Peripheral venous blood for total and differential cell counts.
  • Peripheral blood-serum samples for IL-6, IL-8, C-reactive protein, serum fibrinogen.
  • Collecting blood samples for DNA extraction; to be preserved as archival material for future COPD genetic studies.
  • Study the effects of steroids on key inflammatory parameters selected from this study.


    The duration of the study would be approximately 30 months.

     Expected outcomes

    • Help develop potential new treatments aimed at improving the quality of lives of COPD patients.
    • Strengthen collaborative ties among Imperial College, CRF and VRHP.
    • Encourage exchange programs for mutual growth and development of research in the field of respiratory disorders.
    • Contribute to new knowledge in the field of non-smoking COPD.
    • Influence public health policy decisions in India and other countries with similar health profile.
    • Create a strong India-specific database for future research work.
    • Establish a DNA Bank for future genetic studies in COPD.

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